Friday, October 24, 2025

Time (PT) Talk Speaker
6:00 pm Cocktails
6:30 pm Faculty Dinner
8:00 – 8:30 pm Neurocardiology and Cardiac Neuromodulation: Physiologic Principles and Therapeutic Expectations Kalyanam Shivkumar MD, Olujimi Ajijola MD
8:30 – 9:00 pm Discussion

Saturday, October 25, 2025

Time (PT) Talk Speaker
7:30 am Registration & Vendor Exhibit
7:55 – 8:00 am Welcome & Introduction to the 5th Annual Brain–Heart & Neuromodulation Symposium Robert Lemery MD, Vijay Swarup MD, David Wang DO, Kalyanam Shivkumar MD
Session I — Jeff Ardell & the Human Legacy to the Physiology of the Autonomic Nervous System & the Intrinsic Cardiac Nervous System
Moderators: Kalyanam Shivkumar MD, Olujimi Ajijola MD
8:00 – 8:10 am How About 7 Decades of Contributions to Human Physiology from the Trio of Randall–Ardell–Armour Robert Lemery MD
8:10 – 8:20 am Anatomy of the (Cardiac) Autonomic Nervous System Guru Kowlgi MBBS
8:20 – 8:30 am Physiology of the Extrinsic and Intrinsic Cardiac Nervous System Sunny Po MD
8:30 – 8:40 am Simultaneous Recordings of ECG and Skin Sympathetic Nerve Activity Peng-Sheng Chen MD
8:40 – 8:50 am Jeffrey L. Ardell, PhD.: Translational Neurocardiology. I. Contributions Olujimi Ajijola MD
8:50 – 9:00 am Jeffrey L. Ardell, PhD.: Translational Neurocardiology. II. Advancements Olujimi Ajijola MD
9:00 – 9:10 am Jeffrey L. Ardell, PhD.: Translational Neurocardiology. III. Future Impact Olujimi Ajijola MD
9:10 – 9:30 am Panel Discussion & Q&A
9:30 – 10:00 am Pause and Coffee Break
Session II — Cardiac Neuromodulation Affecting Mostly SYMPATHETIC Innervation
Moderators: Robert Lemery MD, Sunny Po MD
10:00 – 10:10 amCardiac Sympathetic Denervation: Anatomic & Physiologic Principles During Thoracoscopic Surgical Interventions for VT/VFKalyanam Shivkumar MD
10:10 – 10:20 amPsychological and Psychiatric Outcomes Following Stellate Ganglion Block and Cardiac Sympathetic DenervationSahib Khalsa MD
10:20 – 10:30 amSympathetic Tone and Neuropeptide Y: Culprit and FoeOlujimi Ajijola MD
10:30 – 10:40 amSympathetic Nerve Activity and ST-segment DepressionPeng-Sheng Chen MD
10:40 – 10:50 amCardiac Sympathetic Denervation Targeting the Vestigial Fold in HumansKalyanam Shivkumar MD
10:50 – 11:00 amPFA and Thermal Ablation Technologies for Ablation of AF and Different Impacts on Autonomic ToneGuru Kowlgi MBBS
11:00 – 11:10 amEpicardial Delivery of Electroporation on the Cardiac Ganglia: PFA Does Impact Autonomic ToneGuru Kowlgi MBBS
11:10 – 11:30 amPanel Discussion & Q&A
Session III — Atrial Fibrillation & Stroke Prevention Debate
Moderators: Vivek Reddy MD, Dhanunjaya Lakkireddy MD,
11:30 – 11:40 amThe PHARMACOLOGIC Approach: Anticoagulants and Beyond — PROArash Aryana MD
11:40 – 11:50 amThe COMBINED Approach: Catheter Ablation + Left Atrial Appendage Occlusion — PROShephal Doshi MD
11:50 – 12:00 amThe COMBINED Approach: Catheter Ablation + Left Atrial Appendage Occlusion — CONVijay Swarup MD
Lunch — Heart Failure Primer
Moderators: William Resh MD, Sunil Kalla MD
12:10 – 12:20 pm Neuromodulation in Congestive Heart Failure: Carotid Baroreceptor Stimulation and Cardiac Contractility Modulation David Kenigsberg MD
12:20 – 12:30 pm Leadless Pacing for Performing Conduction System Pacing Shephal Doshi MD
12:30 – 12:40 pm Extravascular Implantable Cardioverter-Defibrillator Systems Sudarone Thihalolipavan MD
12:40 – 12:50 pm Amyloid Disease in the Brain and Heart: Stabilizing Transthyretin Protein in Cardiac Amyloidosis Sina Nafisi MD
Session IV — Atrial Fibrillation & the Management of Stroke
Moderators: Supreet Kaur MD, Shephal Doshi MD
1:00 – 1:10 pmHow Modern AF Ablation and LAA physiology are Rewriting Stroke PreventionVijay Swarup MD
1:10 – 1:20 pmEmbolic Strokes of Unknown Source (ESUS): Controversies in Diagnosis, Risk, and TreatmentSupreet Kaur MD
1:20 – 1:30 pmTailored Stroke Prevention in Atrial FibrillationEdip Gurol MD
1:30 – 1:40 pmAtrial Fibrillation & CognitionEdip Gurol MD
1:40 – 1:50 pmMoving Forward: Beyond 30 years of Lytic Treatment for Acute Stroke ManagementDavid Wang DO
1:50 – 2:00 pmLow-Field MRI for Diagnosis of Stroke Care: Revolutionizing Detection, Diagnosis and InterventionDavid Wang DO
2:00 – 2:10 pmThe Ambulatory Surgical Center & The Management of Rhythm Disorders: A New Era in Clinical Cardiac ElectrophysiologyArash Aryana MD
2:10 – 2:30 pmPanel Discussion & Q&A
2:30 – 3:00 pm Pause and Coffee Break
Session V — Cardiac Neuromodulation Affecting Mostly PARASYMPATHETIC Innervation
Moderators: David Kenigsberg MD, David Wang DO
3:00 – 3:10 pmNeuromodulation for Paroxysmal AF. I. Conceptual BasisPeng-Sheng Chen MD
3:10 – 3:20 pmNeuromodulation for AF. II. Tragus Nerve Stimulation & Cardioneural Ablation (Paroxysmal & Post-Operative AF)Sunny Po MD
3:20 – 3:30 pmNeuromodulation for Syncope. I. Conceptual BasisSri Sundaram MD
3:30 – 3:40 pmNeuromodulation for Syncope. II. Cardioneural Ablation — The US Registry TrialSri Sundaram MD
3:40 – 3:50 pmOutcomes of Neuromodulation Interventions: Nuclear Imaging of the Cardiac Autonomic Nervous SystemRobert Lemery MD
3:50 – 4:00 pmCardiac Interoception and NeuromodulationSahib Khalsa MD
4:00 – 4:10 pmCardiac Neuromodulation: A Fine Balancing ActKalyanam Shivkumar MD
4:10 – 4:30 pmPanel Discussion & Q&A
Session VI — NIH & Industry Sponsored Trials: NEW and UPCOMING
Moderators: Vivek Reddy MD, Peng-Sheng Chen MD, Kalyanam Shivkumar MD
4:30 – 4:35 pmResearch Study I
4:35 – 4:40 pmResearch Study II
4:40 – 4:45 pmResearch Study III
4:45 – 4:50 pmResearch Study IV
4:50 – 4:55 pmResearch Study V
4:55 – 5:00 pmSummary
5:00 pm Concluding Remarks Robert Lemery MD, Vijay Swarup MD, David Wang DO, Kalyanam Shivkumar MD
5:05 pm Meeting Adjourns
5:05 – 6:00 pm Refreshments and Snacks

This activity has been planned and implemented by CineMed and Arizona Cardiovascular Research Foundation. CineMed is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

CineMed designates this live activity for 8.00 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity. This educational activity is also approved for 8.00 contact hours for nurses.